Essay

Essay

1. Briefly define the following (i.e., Is it a receptor? If so what type of receptor? etc.) and provide a one sentence description of the biological function or role in the study.
a.     AhR
b.     ApoE-/-
c.     CH223191
d.     CSF
e.     CXCR2
f.      CYP1A1
g.     IL-8
h.     INCB3344
i.      MCP-1
j.      MMP-12
k.     MNF
l.      SB225002
m.   TCDD
n.     U937
o.     VEGF

Why was the above data set included in the paper?
What does it demonstrate?
What is scramble?

Briefly define the following (i.e., Is it a receptor? If so what type of receptor? etc.) and provide a one sentence description of the biological function or role in the study.
a.     Bay 11-7082
b.     CCR2
c.     CXCR3
d.     ERK
e.     IL-6
f.      IL-8
g.     Infliximab
h.     MMP3
i.      NFkappaB
j.      alpha-NP
k.     TNF-alpha
l.      U0126

Which of the following is a correct interpretation of the data in the figure?

Question 4 options:
MMP-9 and MMP-2 are inhibited by the AhR.
IL-1B induces MMP-9 and MMP-2 in an AhR-dependent manner.
Inhibition of the AhR significantly inhibits basal MMP-9 and MMP-2 activity.
The effects of GNF351 are concentration dependent.

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